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0 0.5 1 1.5 2+ Mortality 36% Improvement Relative Risk c19early.com/mf Yang et al. Metformin for COVID-19 META ANALYSIS Favors metformin Favors control
Yang, metformin meta analysis: 36% lower mortality [p<0.0001] https://c19p.org/yang
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The effect of metformin on mortality and severity in COVID-19 patients with diabetes mellitus
Yang et al., Diabetes Research and Clinical Practice, doi:10.1016/j.diabres.2021.108977 (meta analysis)
31 Aug 2021    Source   PDF   Share   Tweet
Meta analysis of 17 studies including 20,719 COVID-19 patients with diabetes, showing lower risk of mortality and severity with metformin.
Currently there are 48 metformin for COVID-19 studies, showing 33% [28‑39%] lower mortality, 40% [17‑57%] lower ventilation, 21% [5‑35%] lower ICU admission, 20% [6‑31%] lower hospitalization, and 0% [-15‑14%] lower cases.
risk of death, 36.0% lower, OR 0.64, p < 0.001, RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Yang et al., 31 Aug 2021, peer-reviewed, 4 authors.
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