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All Studies   Meta Analysis   Recent: 
Timing of REGEN-COV administration and progression to severe COVID-19
Kadowaki et al., Journal of Infection and Chemotherapy, doi:10.1016/j.jiac.2022.07.002
11 Jul 2022    Source   PDF   Share   Tweet
Retrospective 342 patients in Japan, showing significantly greater efficacy of casirivimab/imdevimab with earlier treatment. The proportion of patients progressing to severe COVID-19 increased daily from symptom onset and increased sharply from day 5.
Efficacy is variant dependent. In Vitro research suggests a lack of efficacy for omicron [Liu, Sheward, Tatham, VanBlargan].
Kadowaki et al., 11 Jul 2022, retrospective, Japan, peer-reviewed, 5 authors, study period 19 July, 2021 - 30 September, 2021.
Contact: p5j44x0d@s.okayama-u.ac.jp.
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