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0 0.5 1 1.5 2+ Mortality -24% Improvement Relative Risk c19rmd.com Yeramaneni et al. Remdesivir for COVID-19 LATE Favors remdesivir Favors control
Yeramaneni, 7,158 patient remdesivir late treatment study: 24% higher mortality [p=0.87] https://c19p.org/yeramanenis
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Famotidine Use Is Not Associated With 30-day Mortality: A Coarsened Exact Match Study in 7158 Hospitalized Patients With Coronavirus Disease 2019 From a Large Healthcare System
Yeramaneni et al., Gastroenterology, doi:10.1053/j.gastro.2020.10.011
28 Feb 2021    Source   PDF   Share   Tweet
Retrospective 7,158 hospitalized COVID-19 patients in the USA, showing no significant difference in mortality with remdesivir treatment.
[Gérard, Zhou] show significantly increased risk of acute kidney injury with remdesivir.
risk of death, 24.0% higher, OR 1.24, p = 0.87, treatment 32, control 7,126, adjusted per study, multivariable, RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Yeramaneni et al., 28 Feb 2021, retrospective, USA, peer-reviewed, 6 authors, study period 11 February, 2020 - 8 May, 2020.
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Late treatment
is less effective
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