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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Hospitalization -12% Improvement Relative Risk Case -8% c19early.com/ib Xie et al. Ibuprofen for COVID-19 Prophylaxis Favors ibuprofen Favors other NSAIDs
Xie, 1,697,522 patient ibuprofen prophylaxis study: 12% higher hospitalization [p=0.26] and 8% more cases [p=0.25] https://c19p.org/xieib
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Risk of COVID-19 Diagnosis and Hospitalization in Patients with Osteoarthritis or Back Pain Treated with Ibuprofen Compared to Other NSAIDs or Paracetamol: A Network Cohort Study
Xie et al., SSRN Electronic Journal, doi:10.2139/ssrn.4161710
13 Jul 2022    Source   PDF   Share   Tweet
PSM retrospective 1,697,522 osteoarthritis or back pain patients in the US, showing no significant differences in COVID-19 cases and hospitalization for ibuprofen vs. other NSAIDs.
risk of hospitalization, 12.5% higher, HR 1.12, p = 0.26, Open Claims, PharMetrics Plus, both periods combined.
risk of case, 7.6% higher, HR 1.08, p = 0.25, Open Claims, PharMetrics Plus, both periods combined.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Xie et al., 13 Jul 2022, retrospective, USA, peer-reviewed, 9 authors, study period 1 February, 2020 - 31 October, 2020, this trial compares with another treatment - results may be better when compared to placebo.
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