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Home   COVID-19 treatment studies for Indomethacin  COVID-19 treatment studies for Indomethacin  C19 studies: Indomethacin  Indomethacin   Select treatmentSelect treatmentTreatmentsTreatments
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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Oxygen therapy 96% Improvement Relative Risk Recovery time 43% Recovery time (b) 54% Recovery time (c) 62% c19early.com/in Ravichandran et al. ISRCTN 11970082 Indomethacin LATE Favors indomethacin Favors paracetamol
Ravichandran, 144 patient indomethacin late treatment PSM study: 96% lower need for oxygen therapy [p<0.0001] and 43% faster recovery [p<0.0001] https://c19p.org/ravichandran2
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Use of indomethacin in COVID-19 patients: experience from two medical centres
Ravichandran et al., J. Indian Med. Assoc., 119:7, ISRCTN11970082
31 Jul 2021    Source   PDF   Share   Tweet
PSM retrospective 72 indomethacin and 72 paracetamol patients in India, showing lower progression and improved recovery with indomethacin.
risk of oxygen therapy, 96.4% lower, RR 0.04, p < 0.001, treatment 1 of 72 (1.4%), control 28 of 72 (38.9%), NNT 2.7, propensity score matching.
recovery time, 42.9% lower, relative time 0.57, p < 0.001, treatment median 4.0 IQR 1.0 n=72, control median 7.0 IQR 1.0 n=72, fever.
recovery time, 53.8% lower, relative time 0.46, p < 0.001, treatment median 3.0 IQR 2.0 n=72, control median 6.5 IQR 3.25 n=72, myalgia.
recovery time, 62.5% lower, relative time 0.38, p < 0.001, treatment median 3.0 IQR 2.0 n=72, control median 8.0 IQR 2.0 n=72, cough.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Ravichandran et al., 31 Jul 2021, retrospective, India, peer-reviewed, 6 authors, this trial compares with another treatment - results may be better when compared to placebo, trial ISRCTN11970082.
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This PaperIndomethacinAll
Late treatment
is less effective
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