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0 0.5 1 1.5 2+ Mortality -40% unadjusted Improvement Relative Risk c19early.com/s Oku et al. Remdesivir for COVID-19 LATE TREATMENT Favors remdesivir Favors control
Oku, 218 patient remdesivir late treatment study: 40% higher mortality [p=0.59] https://c19p.org/okus
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Risk factors for hospitalization or mortality for COVID-19 in patients with rheumatic diseases: Results of a nation-wide JCR COVID-19 registry in Japan
Oku et al., Modern Rheumatology, doi:10.1093/mr/roac104
6 Sep 2022    Source   PDF   Share   Tweet
Retrospecttive 220 COVID-19 patients with rheumatic disease in Japan, showing no significant difference in mortality with remdesivir treatment.
[Gérard, Zhou] show significantly increased risk of acute kidney injury with remdesivir.
risk of death, 40.2% higher, RR 1.40, p = 0.59, treatment 3 of 46 (6.5%), control 8 of 172 (4.7%), unadjusted, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details.
Oku et al., 6 Sep 2022, retrospective, Japan, peer-reviewed, 8 authors, study period 3 June, 2020 - 30 June, 2021.
Contact: horiuchi.takahiko.191@m.kyushu-u.ac.jp.
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This PaperRemdesivirAll
Late treatment
is less effective
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