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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Unresolved fever 25% Improvement Relative Risk Unresolved fatigue 33% Unresolved cough 0% Unresolved headache 0% Unresolved loss of smell.. 25% c19early.com/lf Algahtani et al. Lactoferrin for COVID-19 RCT LATE Favors lactoferrin Favors control
Algahtani, 54 patient lactoferrin late treatment RCT: 25% improved recovery [p=1] https://c19p.org/algahtani
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The Prospect of Lactoferrin Use as Adjunctive Agent in Management of SARS-CoV-2 Patients: A Randomized Pilot Study
Algahtani et al., Medicina, doi:10.3390/medicina57080842
19 Aug 2021    Source   PDF   Share   Tweet
RCT 54 hospitalized patients in Egypt, showing no significant differences in recovery with lactoferrin treatment. 200mg lactoferrin orally once daily (group 1) or 200mg lactoferrin orally twice daily (group 2).
risk of unresolved fever, 25.0% lower, RR 0.75, p = 1.00, treatment 3 of 36 (8.3%), control 2 of 18 (11.1%), NNT 36, day 7.
risk of unresolved fatigue, 33.3% lower, RR 0.67, p = 0.67, treatment 4 of 36 (11.1%), control 3 of 18 (16.7%), NNT 18, day 7.
risk of unresolved cough, no change, RR 1.00, p = 1.00, treatment 8 of 36 (22.2%), control 4 of 18 (22.2%), day 7.
risk of unresolved headache, no change, RR 1.00, p = 1.00, treatment 4 of 36 (11.1%), control 2 of 18 (11.1%), day 7.
risk of unresolved loss of smell/taste, 25.0% lower, RR 0.75, p = 0.72, treatment 6 of 36 (16.7%), control 4 of 18 (22.2%), NNT 18, day 7.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Algahtani et al., 19 Aug 2021, Randomized Controlled Trial, Egypt, peer-reviewed, 6 authors, study period 8 July, 2020 - 18 September, 2020.
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Late treatment
is less effective
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