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0 0.5 1 1.5 2+ Mortality 91% Improvement Relative Risk Severe case 70% c19early.com/ex Yuan et al. Exercise for COVID-19 Prophylaxis Favors exercise Favors inactivity
Yuan, 164 patient exercise study: 91% lower mortality [p=0.09] and 70% lower severe cases [p=0.03] https://c19p.org/yuan2
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Does pre-existent physical inactivity have a role in the severity of COVID-19?
Yuan et al., Therapeutic Advances in Respiratory Disease, doi:10.1177/17534666211025221
20 Jun 2021    Source   PDF   Share   Tweet
Retrospective 164 COVID-19 patients in China, showing physical inactivity associated with an increased risk of severe COVID-19.
risk of death, 90.5% lower, RR 0.09, p = 0.09, high activity levels 0 of 61 (0.0%), low activity levels 6 of 103 (5.8%), NNT 17, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm), excluded in exclusion analyses: excessive unadjusted differences between groups.
risk of severe case, 70.0% lower, RR 0.30, p = 0.03, high activity levels 3 of 61 (4.9%), low activity levels 26 of 103 (25.2%), NNT 4.9, adjusted per study, inverted to make RR<1 favor high activity levels, odds ratio converted to relative risk, multivariable.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Yuan et al., 20 Jun 2021, retrospective, China, peer-reviewed, 9 authors, study period 15 February, 2020 - 14 March, 2020.
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