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0 0.5 1 1.5 2+ Mortality 51% Improvement Relative Risk Mortality (b) -59% late c19early.com/fm Yeramaneni et al. Famotidine for COVID-19 Prophylaxis Favors famotidine Favors control
Yeramaneni, 7,158 patient famotidine prophylaxis study: 51% lower mortality [p=0.22] https://c19p.org/yeramaneni
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Famotidine Use Is Not Associated With 30-day Mortality: A Coarsened Exact Match Study in 7158 Hospitalized Patients With Coronavirus Disease 2019 From a Large Healthcare System
Yeramaneni et al., Gastroenterology, doi:10.1053/j.gastro.2020.10.011
28 Feb 2021    Source   PDF   Share   Tweet
Retrospective 7,158 hospitalized COVID-19 patients in the USA, showing higher risk or mortality with in-hospital famotidine use and lower risk with pre-existing use, without statistical significance in both cases.
risk of death, 51.0% lower, OR 0.49, p = 0.22, treatment 351, control 6,807, adjusted per study, home use, multivariable, RR approximated with OR.
risk of death, 59.0% higher, OR 1.59, p = 0.09, treatment 410, control 746, adjusted per study, hospital use, multivariable, RR approximated with OR, late treatment result.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Yeramaneni et al., 28 Feb 2021, retrospective, USA, peer-reviewed, 6 authors, study period 11 February, 2020 - 8 May, 2020.
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