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0 0.5 1 1.5 2+ Death/ICU 76% Improvement Relative Risk c19early.com/va Voelkle et al. Vitamin A for COVID-19 Sufficiency Favors vitamin A Favors control
Voelkle, 57 patient vitamin A sufficiency study: 76% lower combined mortality/ICU admission [p=0.004] https://c19p.org/voelkleva
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Prevalence of Micronutrient Deficiencies in Patients Hospitalized with COVID-19: An Observational Cohort Study
Voelkle et al., Nutrients, doi:10.3390/nu14091862
30 Apr 2022    Source   PDF   Share   Tweet
Prospective study of 57 consecutive hospitalized COVID-19 patients in Switzerland, showing higher risk of mortality/ICU admission with vitamin A, vitamin D, and zinc deficiency, with statistical significance only for vitamin A and zinc. Adjustments only considered age.
risk of death/ICU, 76.2% lower, RR 0.24, p = 0.004, treatment 4 of 35 (11.4%), control 11 of 22 (50.0%), NNT 2.6, adjusted per study, inverted to make RR<1 favor treatment, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Voelkle et al., 30 Apr 2022, prospective, Switzerland, peer-reviewed, median age 67.0, 9 authors, study period 17 March, 2020 - 30 April, 2020.
Contact: schuetzph@gmail.com (corresponding author), manyola.voelkle@ksa.ch, claudia.gregoriano@ksa.ch, daniel.koch@ksa.ch, alexander.kutz@ksa.ch, beat.mueller@ksa.ch, anna.conen@ksa.ch, peter.neyer@ksa.ch, luca.bernasconi@ksa.ch.
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