0
0.5
1
1.5
2+
Mortality
55%
Improvement
Relative Risk
Ventilation
34%
ICU admission
19%
Recovery
47%
Spironolactone Abbasi et al. LATE TREATMENT RCT
Is late treatment with antiandrogens beneficial for COVID-19?
RCT 138 patients in Iran (December 2020 - April 2021)
Improved recovery with antiandrogens (p=0.000059)
c19early.org
Abbasi et al., J. the Endocrine Society, Feb 2022
Favors spironolactone
Favors control