Simova, 38 patient HCQ early treatment study: 94% lower hospitalization [p=0.01] and 96% improved viral clearance [p=0.001] https://c19p.org/simova
copied to clipboard
Hydroxychloroquine for prophylaxis and treatment of COVID-19 in health care workers
et al., New Microbes and New Infections, doi:10.1016/j.nmni.2020.100813
100% reduction in hospitalization and cases with early treatment using HCQ+AZ+zinc. Brief report on healthcare workers in Bulgaria.0 hospitalizations with treatment vs. 2 for control
0 PCR+ at day 14 with treatment vs. 3 for control33 treatment patients and 5 control patients.No serious adverse events. This paper reports on both PEP and early treatment, we have separated the two studies.
0 PCR+ at day 14 with treatment vs. 3 for control33 treatment patients and 5 control patients.No serious adverse events. This paper reports on both PEP and early treatment, we have separated the two studies.
|
risk of hospitalization, 93.8% lower, RR 0.06, p = 0.01, treatment 0 of 33 (0.0%), control 2 of 5 (40.0%), NNT 2.5, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
|
|
risk of viral+ at day 14, 95.8% lower, RR 0.04, p = 0.001, treatment 0 of 33 (0.0%), control 3 of 5 (60.0%), NNT 1.7, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
|
| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Simova et al., 11/12/2020, retrospective, Bulgaria, peer-reviewed, 5 authors, dosage 200mg tid days 1-14, this trial uses multiple treatments in the treatment arm (combined with AZ and zinc) - results of individual treatments may vary.
Please send us corrections, updates, or comments. Vaccines and
treatments are both valuable and complementary. All practical, effective, and
safe means should be used. No treatment, vaccine, or intervention is 100%
available and effective for all current and future variants. Denying the
efficacy of any method increases mortality, morbidity, collateral damage, and
the risk of endemic status. We do not provide medical advice. Before taking
any medication, consult a qualified physician who can provide personalized
advice and details of risks and benefits based on your medical history and
situation. FLCCC and WCH
provide treatment protocols.