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Home   COVID-19 treatment studies for Convalescent Plasma  COVID-19 treatment studies for Conv. Plasma  C19 studies: Conv. Plasma  Conv. Plasma   Select treatmentSelect treatmentTreatmentsTreatments
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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mortality 33% primary Improvement Relative Risk c19early.com/ray.html Favors conv. plasma Favors control
29 November 2020 - Late treatment study
Clinical and immunological benefits of convalescent plasma therapy in severe COVID-19: insights from a single center open label randomised control trial
Ray et al., medRxiv, doi:10.1101/2020.11.25.20237883 (Peer Reviewed)
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Small RCT 80 hospitalized patients in India, 40 treated with convalescent plasma, not showing significant differences in primary analysis. Authors note that significant improvement in hypoxia, reduction in hospital stay, and survival benefit was seen in severe COVID-19 patients with ARDS aged <67. CTRI/2020/05/025209.
risk of death, 33.0% lower, RR 0.67, p = 0.34, treatment 10 of 40 (25.0%), control 14 of 40 (35.0%), NNT 10, adjusted per study, Mantel-Haenszel.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Ray et al., 11/29/2020, Randomized Controlled Trial, India, South Asia, peer-reviewed, 37 authors.
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