Database of all paxlovid COVID-19 studies. PAXLOVID™ is an investigational SARS-CoV-2 protease inhibitor antiviral therapy combining PF-07321332 and ritonavir. Submit updates/
|Animal||doi:10.1101/2021.11.04.467077 (Preprint)et al., bioRxiv,||
|The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern|
|Details In Vitro and hamster study showing paxlovid component PF-07321332 effective against four variants of concern, inibits replication of the alpha variant in primary human airway epithelial cells, protected Syrian hamsters against intranasal ..|
|Early||Press Release (News)||
death, ↓95.2%, p=0.002
|Pfizer's novel COVID-19 oral antiviral treatment candidate reduced risk of hospitalization or death by 89% in interim analysis of phase 2/3 EPIC-HR study|
|Details Interim analysis of EPIC-HR, 607 higher risk patients treated with paxlovid (PF-07321332 + ritonavir) and 612 control patients, showing significantly lower mortality and hospitalization with treatment.|
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