Patel, 58 patient various antiandrogen prophylaxis study: 55% lower mortality [p=0.22], 69% lower ventilation [p=0.19], and 77% lower hospitalization [p=0.02] https://c19p.org/patel3
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Does androgen deprivation therapy protect against severe complications from COVID-19?
et al., Annals of Oncology, doi:10.1016/j.annonc.2020.06.023
Retrospective 58 prostate cancer patients in the USA, showing lower risk of hospitalization with ADT.
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risk of death, 55.2% lower, RR 0.45, p = 0.22, treatment 4 of 22 (18.2%), control 10 of 36 (27.8%), adjusted per study, odds ratio converted to relative risk, multivariable.
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risk of mechanical ventilation, 69.0% lower, OR 0.31, p = 0.19, treatment 22, control 36, adjusted per study, multivariable, RR approximated with OR.
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risk of hospitalization, 77.0% lower, OR 0.23, p = 0.02, treatment 22, control 36, adjusted per study, multivariable, RR approximated with OR.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Patel et al., 9 Jul 2020, retrospective, USA, peer-reviewed, 7 authors, study period 1 March, 2020 - 4 June, 2020.
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