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0 0.5 1 1.5 2+ Severe case or mortality 46% Improvement Relative Risk c19early.com/pl Najjar-Debbiny et al. Paxlovid for COVID-19 EARLY Favors paxlovid Favors control
Najjar-Debbiny, 180,351 patient paxlovid early treatment study: 46% lower severe cases [p=0.0002] https://c19p.org/najjardebbiny
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Effectiveness of Paxlovid in Reducing Severe COVID-19 and Mortality in High Risk Patients
Najjar-Debbiny et al., Clinical Infectious Diseases, doi:10.1093/cid/ciac443
2 Jun 2022    Source   PDF   Share   Tweet
Retrospective 180,351 patients in Israel, 4,737 treated with paxlovid, showing significantly lower combined severe COVID-19 / mortality with treatment.
risk of severe case or mortality, 46.0% lower, HR 0.54, p < 0.001, treatment 4,737, control 175,614, adjusted per study, multivariable, Cox proportional hazards.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Najjar-Debbiny et al., 6/2/2022, retrospective, Israel, Middle East, peer-reviewed, 8 authors, study period 1 January, 2022 - 28 February, 2022.
Contact: ronzana@clalit.org.il, ronza.najjar@gmail.com.
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