Merino, 296,285 patient diet study: 41% lower severe cases [p<0.0001] and 18% fewer cases [p<0.0001] https://c19p.org/merino2
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Diet quality and risk and severity of COVID-19: a prospective cohort study
et al., Gut, doi:10.1136/gutjnl-2021-325353 (date from earlier preprint)
Retrospective 592,571 participants in the UK and USA with 31,815 COVID-19 cases, showing lower risk or COVID-19 cases and severity for higher healthful plant-based diet scores. Notably, the assocation was less evident with higher levels of physical activity.
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risk of severe case, 41.0% lower, HR 0.59, p < 0.001, higher quality diet 148,142, lower quality diet 148,143, adjusted per study, model 3, high vs. low hPDI, multivariable, Cox proportional hazards.
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risk of case, 18.0% lower, HR 0.82, p < 0.001, higher quality diet 148,142, lower quality diet 148,143, adjusted per study, model 3, high vs. low hPDI, PCR+, multivariable, Cox proportional hazards.
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risk of case, 9.0% lower, HR 0.91, p < 0.001, higher quality diet 148,142, lower quality diet 148,143, adjusted per study, model 3, high vs. low hPDI, multivariable, Cox proportional hazards.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Merino et al., 25 Jun 2021, retrospective, multiple countries, peer-reviewed, survey, 30 authors, study period 24 March, 2020 - 2 December, 2020.
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