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Home   COVID-19 treatment studies for Bamlanivimab/etesevimab  COVID-19 treatment studies for Bamlaniv../e..  C19 studies: Bamlaniv../e..  Bamlaniv../e..   Select treatmentSelect treatmentTreatmentsTreatments
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0 0.5 1 1.5 2+ Symptomatic case 57% Improvement Relative Risk Symptomatic case (b) 80% c19ly.com Lilly et al. Bamlaniv../e.. for COVID-19 RCT Prophylaxis Favors bamlanivimab/e.. Favors control
Lilly, 965 patient bamlanivimab/etesevimab prophylaxis RCT: 57% fewer symptomatic cases [p=0.0002] https://c19p.org/lilly3
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Lilly's neutralizing antibody bamlanivimab (LY-CoV555) prevented COVID-19 at nursing homes in the BLAZE-2 trial, reducing risk by up to 80 percent for residents
Lilly, Press Release (Preprint)
21 Jan 2021    Source   PDF   Share   Tweet
Press release on the BLAZE-2 trial at nursing homes showing significantly lower symptomatic COVID-19 with treatment.
Efficacy is highly variant dependent. In Vitro research suggests a lack of efficacy for omicron [Liu, Sheward, VanBlargan].
risk of symptomatic case, 57.0% lower, RR 0.43, p < 0.001, treatment 483, control 482, group sizes estimated because they were not supplied.
risk of symptomatic case, 80.0% lower, RR 0.20, p < 0.001, treatment 150, control 149, nursing home residents, group sizes estimated because they were not supplied.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Lilly et al., 21 Jan 2021, Randomized Controlled Trial, USA, preprint, 1 author.
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