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0 0.5 1 1.5 2+ Case 3% Improvement Relative Risk c19early.com/ib Leal et al. Ibuprofen for COVID-19 Prophylaxis Favors ibuprofen Favors control
Leal, ibuprofen prophylaxis study: 3% fewer cases [p=0.29] https://c19p.org/lealib
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Paracetamol Is Associated with a Lower Risk of COVID-19 Infection and Decreased ACE2 Protein Expression: A Retrospective Analysis
Leal et al., COVID, doi:10.3390/covid1010018
16 Aug 2021    Source   PDF   Share   Tweet
UK Biobank retrospective showing no significant difference in cases with ibuprofen use.
risk of case, 3.0% lower, OR 0.97, p = 0.29, RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Leal et al., 16 Aug 2021, retrospective, United Kingdom, peer-reviewed, 5 authors, study period 16 March, 2020 - 1 February, 2021.
Contact: martins.lmiguel@gmail.com (corresponding author), njs76@mrc-tox.cam.ac.uk, yzy21@cam.ac.uk, yc487@cam.ac.uk, gf334@mrc-tox.cam.ac.uk.
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