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0 0.5 1 1.5 2+ Mortality 52% Improvement Relative Risk c19early.com/mf Lally et al. Metformin for COVID-19 Prophylaxis Favors metformin Favors control
Lally, 775 patient metformin prophylaxis study: 52% lower mortality [p=0.009] https://c19p.org/lally
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Metformin is Associated with Decreased 30-Day Mortality Among Nursing Home Residents Infected with SARS-CoV2
Lally et al., Journal of the American Medical Directors Association, doi:10.1016/j.jamda.2020.10.031
31 Jan 2021    Source   PDF   Share   Tweet
Retrospective 775 nursing home residents in the USA, showing lower mortality with existing metformin use.
risk of death, 52.0% lower, HR 0.48, p = 0.009, treatment 16 of 127 (12.6%), control 144 of 648 (22.2%), NNT 10, adjusted per study, multivariable regression.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Lally et al., 1/31/2021, retrospective, USA, North America, peer-reviewed, 6 authors.
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