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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Mortality 46% Improvement Relative Risk Death/ICU 46% Case 11% c19early.com/aa Koskinen et al. Antiandrogens for COVID-19 Prophylaxis Favors antiandrogen Favors control
Koskinen, 352 patient various antiandrogen prophylaxis study: 46% lower mortality [p=1], 46% lower combined mortality/ICU admission [p=1], and 11% fewer cases [p=1] https://c19p.org/koskinen
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Androgen deprivation and SARS-CoV-2 in men with prostate cancer
Koskinen et al., Annals of Oncology, doi:10.1016/j.annonc.2020.06.015
29 Jun 2020    Source   PDF   Share   Tweet
Retrospective 352 prostate cancer patients in Finland, showing no significant differences in COVID-19 with ADT.
risk of death, 45.8% lower, RR 0.54, p = 1.00, treatment 1 of 134 (0.7%), control 3 of 218 (1.4%), NNT 159.
risk of death/ICU, 45.8% lower, RR 0.54, p = 1.00, treatment 1 of 134 (0.7%), control 3 of 218 (1.4%), NNT 159.
risk of case, 11.3% lower, RR 0.89, p = 1.00, treatment 6 of 134 (4.5%), control 11 of 218 (5.0%), NNT 176.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Koskinen et al., 6/29/2020, retrospective, Finland, Europe, peer-reviewed, 7 authors.
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