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0 0.5 1 1.5 2+ Hospitalization -229% Improvement Relative Risk Case 29% c19early.com/aa Kazan et al. Antiandrogens for COVID-19 Prophylaxis Favors various Favors control
Kazan, 365 patient various antiandrogen prophylaxis study: 229% higher hospitalization [p=0.2] and 29% fewer cases [p=0.32] https://c19p.org/kazan
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The clinical impact of androgen deprivation therapy on SARS-CoV-2 infection rates and disease severity
Kazan et al., Türk Üroloji Dergisi/Turkish Journal of Urology, doi:10.5152/tud.2021.21278
1 Nov 2021    Source   PDF   Share   Tweet
Retrospective 365 prostate cancer patients in Turkey, 138 treated with ADT, showing no significant differences with treatment.
risk of hospitalization, 229.0% higher, RR 3.29, p = 0.20, treatment 4 of 138 (2.9%), control 2 of 227 (0.9%).
risk of case, 28.7% lower, RR 0.71, p = 0.32, treatment 13 of 138 (9.4%), control 30 of 227 (13.2%), NNT 26.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: excessive unadjusted differences between groups.
Kazan et al., 1 Nov 2021, retrospective, Turkey, peer-reviewed, 10 authors, study period August 2020 - June 2021.
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