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0 0.5 1 1.5 2+ Hospitalization 38% Improvement Relative Risk c19early.com/aa Israel et al. Dutasteride for COVID-19 Prophylaxis Favors dutasteride Favors control
Israel, 39,180 patient dutasteride antiandrogen prophylaxis study: 38% lower hospitalization [p=0.01] https://c19p.org/israel2aa
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Identification of drugs associated with reduced severity of COVID-19: A case-control study in a large population
Israel et al., Epidemiology and Global Health Microbiology and Infectious Disease, doi:10.7554/eLife.68165
27 Jul 2021    Source   PDF   Share   Tweet
Case control study examining medication usage with a healthcare database in Israel, showing lower risk of hospitalization with dutasteride.
risk of hospitalization, 37.7% lower, OR 0.62, p = 0.01, treatment 30 of 6,530 (0.5%) cases, 240 of 32,650 (0.7%) controls, NNT 18, case control OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Israel et al., 7/27/2021, retrospective, Israel, Middle East, peer-reviewed, 10 authors.
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