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All Studies   Meta Analysis    Recent:   

Vitamin C and COVID-19

Hemilä et al., Frontiers in Medicine, doi:10.3389/fmed.2020.559811
Jan 2021  
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Vitamin C for COVID-19
7th treatment shown to reduce risk in September 2020
 
*, now known with p = 0.00000011 from 68 studies, recognized in 10 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
3,900+ studies for 60+ treatments. c19early.org
Review of the use of vitamin C for infections and the potential benefit for COVID-19.
Reviews covering vitamin C for COVID-19 include Arora, Biancatelli, Feyaerts, Foshati, Hemilä, Hemilä (B), Holford, May, Schloss, Yamasaki.
Hemilä et al., 18 Jan 2021, peer-reviewed, 2 authors.
This PaperVitamin CAll
Vitamin C and COVID-19
Harri Hemilä, Angelique M E De Man
Frontiers in Medicine, doi:10.3389/fmed.2020.559811
In numerous animal studies, vitamin C has prevented and alleviated viral and bacterial infections. In a few dozen placebo-controlled trials with humans, vitamin C has shortened infections caused by respiratory viruses, which indicates that the vitamin can also influence viral infections in humans. In critically ill patients, plasma vitamin C levels are commonly very low. Gram doses of vitamin C are needed to increase the plasma vitamin C levels of critically ill patients to the levels of ordinary healthy people. A meta-analysis of 12 trials with 1,766 patients calculated that vitamin C reduced the length of ICU stay on average by 8%. Another meta-analysis found that vitamin C shortened the duration of mechanical ventilation in ICU patients. Two randomized placebo-controlled trials found statistically significant reduction in the mortality of sepsis patients. The effects of vitamin C on acute respiratory distress syndrome (ARDS) frequently complicating COVID-19 pneumonia should be considered. Vitamin C is a safe and inexpensive essential nutrient.
AUTHOR CONTRIBUTIONS HH and AM participated in the revision of the manuscript. Conflict of Interest: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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