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Home   COVID-19 treatment studies for Vitamin C  COVID-19 treatment studies for Vitamin C  C19 studies: Vitamin C  Vitamin C   Select treatmentSelect treatmentTreatmentsTreatments
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0 0.5 1 1.5 2+ Mortality 44% Improvement Relative Risk Hospitalization time 38% c19vitaminc.com Hamidi-Alamdari et al. NCT04370288 Vitamin C RCT LATE Favors vitamin C Favors control
Hamidi-Alamdari, 80 patient vitamin C late treatment RCT: 44% lower mortality [p=0.38] and 38% shorter hospitalization [p=0.004] https://c19p.org/hamidialamdari
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Methylene blue for treatment of hospitalized COVID-19 patients: a randomized, controlled, open-label clinical trial, phase 2
Hamidi-Alamdari et al., Clinical and Translational Investigation, doi:10.24875/RIC.21000028, NCT04370288 (history)
8 Mar 2021    Source   PDF   Share   Tweet
RCT 80 hospitalized patients with severe COVID-19, 40 treated with methylene blue + vitamin C + N-acetylcysteine, showing lower mortality, shorter hospitalization, and significantly improved SpO2 and respiratory distress with treatment. NCT04370288 (history).
risk of death, 44.4% lower, RR 0.56, p = 0.38, treatment 5 of 40 (12.5%), control 9 of 40 (22.5%), NNT 10.0.
hospitalization time, 37.6% lower, relative time 0.62, p = 0.004, treatment 40, control 40.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Hamidi-Alamdari et al., 8 Mar 2021, Randomized Controlled Trial, Iran, peer-reviewed, 23 authors, this trial uses multiple treatments in the treatment arm (combined with methylene blue and N-acetyl cysteine) - results of individual treatments may vary, trial NCT04370288 (history).
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This PaperVitamin CAll
Late treatment
is less effective
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