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0 0.5 1 1.5 2+ Progression -225% Improvement Relative Risk c19early.com/mf Gao et al. Metformin for COVID-19 Prophylaxis Favors metformin Favors control
Gao, 110 patient metformin prophylaxis study: 225% higher progression [p=0.05] https://c19p.org/gao4
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Risk of Metformin in Patients With Type 2 Diabetes With COVID‐19: A Preliminary Retrospective Report
Gao et al., Clinical and Translational Science, doi:10.1111/cts.12897
19 Oct 2020    Source   PDF   Share   Tweet
Retrospective 110 hospitalized COVID-19 patients with diabetes in China, showing increased risk of severity with metformin.
risk of progression, 225.0% higher, RR 3.25, p = 0.045, treatment 16 of 56 (28.6%), control 4 of 54 (7.4%), odds ratio converted to relative risk, progression to life threatening complications.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Gao et al., 19 Oct 2020, retrospective, China, peer-reviewed, 7 authors, study period 31 January, 2020 - 20 March, 2020.
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