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0 0.5 1 1.5 2+ Death/intubation 57% Improvement Relative Risk c19early.com/fm Freedberg et al. Famotidine for COVID-19 Prophylaxis Favors famotidine Favors control
Freedberg, 1,620 patient famotidine prophylaxis PSM study: 57% lower combined mortality/intubation [p=0.02] https://c19p.org/freedberg
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Famotidine Use Is Associated With Improved Clinical Outcomes in Hospitalized COVID-19 Patients: A Propensity Score Matched Retrospective Cohort Study
Freedberg et al., Gastroenterology, doi:10.1053/j.gastro.2020.05.053
21 May 2020    Source   PDF   Share   Tweet
PSM retrospective 1,620 hospitalized patients in the USA, 84 with existing famotidine use, showing lower risk of combined death/intubation with treatment.
risk of death/intubation, 57.0% lower, RR 0.43, p = 0.02, treatment 8 of 84 (9.5%), control 332 of 1,536 (21.6%), NNT 8.3, propensity score matching.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Freedberg et al., 21 May 2020, retrospective, propensity score matching, USA, peer-reviewed, 15 authors.
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