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22 famotidine COVID-19 controlled studies, 3 RCTs
48% improvement
for early treatment, RR
0.52
[0.20-1.32]
https://c19early.com/fmmeta.html
0
0.25
0.5
0.75
1
1.25
1.5
1.75
2+
Brennan (DB RCT)
48%
0.52 [0.20-1.32]
no recov.
5/27
10/28
Improvement, RR [CI]
Treatment
Control
Brennan (DB RCT)
43%
0.57 [0.21-1.55]
no recov.
4/19
10/27
Brennan (DB RCT)
28%
0.72 [0.56-0.92]
recov. time
27 (n)
28 (n)
Shoaibi
-3%
1.03 [0.89-1.18]
death
1,816 (n)
26,820 (n)
Shoaibi
-3%
1.03 [0.92-1.15]
death/ICU
1,816 (n)
26,820 (n)
Zhou (PSM)
-81%
1.81 [1.28-2.58]
severe case
72/519
198/2,595
Yeramaneni
-59%
1.59 [0.94-2.71]
death
410 (n)
746 (n)
Mura (PSM)
21%
0.79 [0.65-0.96]
death
563 (n)
563 (n)
Mura (PSM)
37%
0.63 [0.47-0.83]
death
305 (n)
305 (n)
Samim.. (SB RCT)
33%
0.67 [0.45-0.98]
hosp. time
10 (n)
10 (n)
Samim.. (SB RCT)
0%
1.00 [0.42-2.40]
no recov.
5/10
5/10
Samim.. (SB RCT)
50%
0.50 [0.17-1.46]
no recov.
3/10
6/10
Elhadi (ICU)
7%
0.93 [0.73-1.17]
death
34/60
247/405
ICU patients
Taşdemir
45%
0.55 [0.20-1.55]
death
5/85
10/94
OT1
Taşdemir
37%
0.63 [0.28-1.43]
ICU
8/85
14/94
OT1
Taşdemir
18%
0.82 [0.72-0.93]
hosp. time
85 (n)
94 (n)
OT1
Taşdemir
20%
0.80 [0.65-0.99]
recov. time
85 (n)
94 (n)
OT1
Kuno (PSM)
0%
1.00 [0.86-1.17]
death
1,593 (n)
7,972 (n)
Stolow
-519%
6.19 [2.10-18.3]
death
137 (n)
352 (n)
Stolow
-2390%
24.90 [3.70-168]
ICU
137 (n)
352 (n)
Wagner
70%
0.30 [0.20-0.44]
death
638 (n)
819 (n)
Pahwani (RCT)
11%
0.89 [0.36-2.20]
death
8/89
9/89
Pahwani (RCT)
12%
0.88 [0.53-1.45]
ventilation
21/89
24/89
Pahwani (RCT)
10%
0.90 [0.51-1.58]
ICU
18/89
20/89
Pahwani (RCT)
17%
0.83 [0.79-0.89]
hosp. time
89 (n)
89 (n)
Pahwani (RCT)
10%
0.90 [0.85-0.96]
recov. time
89 (n)
89 (n)
Siraj
36%
0.64 [0.48-0.83]
death
183/711
122/289
Freedberg (PSM)
57%
0.43 [0.21-0.86]
death/int.
8/84
332/1,536
Mather (PSM)
61%
0.39 [0.20-0.74]
death
83 (n)
689 (n)
Mather (PSM)
50%
0.49 [0.31-0.79]
death/int.
83 (n)
689 (n)
Balouch
22%
0.78 [0.36-1.51]
symp. case
18/80
49/227
Balouch
37%
0.63 [0.26-1.54]
recov. time
80 (n)
227 (n)
Yeramaneni
51%
0.49 [0.16-1.52]
death
351 (n)
6,807 (n)
Cheung
-34%
1.34 [0.24-6.06]
severe case
23 (n)
929 (n)
Fung
0%
1.00 [0.96-1.04]
death
population-based cohort
Fung
6%
0.94 [0.91-0.97]
hosp.
population-based cohort
Fung
-12%
1.12 [1.10-1.15]
cases
population-based cohort
Razjouyan
27%
0.73 [0.59-0.92]
death
93 (n)
9,981 (n)
Wallace
-11%
1.11 [0.89-1.35]
death
98/423
1,436/7,521
MacFadden
7%
0.93 [0.84-1.03]
cases
n/a
n/a
famotidine COVID-19 outcomes
c19early.com/fm May 2022
1 OT: comparison with other treatment
Favors famotidine
Favors control
Please send us corrections, updates, or comments. Vaccines and
treatments are both valuable and complementary. All practical, effective, and
safe means should be used. No treatment, vaccine, or intervention is 100%
available and effective for all current and future variants. Denying the
efficacy of any method increases mortality, morbidity, collateral damage, and
the risk of endemic status. We do not provide medical advice. Before taking
any medication, consult a qualified physician who can provide personalized
advice and details of risks and benefits based on your medical history and
situation.
FLCCC and
WCH
provide treatment protocols.
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