Prospective study of 206 outpatients in Iran, 103 treated with spironolactone and sitagliptin, showing lower hospitalization and faster recovery with treatment. spironolactone 100mg and sitagliptin 100mg daily.
risk of hospitalization, 78.3% lower, RR 0.22, p < 0.001, treatment 6 of 103 (5.8%), control 23 of 103 (22.3%), NNT 6.1, odds ratio converted to relative risk.
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recovery time, 64.4% lower, relative time 0.36, p < 0.001, treatment 103, control 103.
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Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
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Davarpanah et al., 1/21/2022, prospective, Iran, Middle East, preprint, 9 authors, study period July 2021 - September 2021, average treatment delay 5.74 days, this trial uses multiple treatments in the treatment arm (combined with sitagliptin) - results of individual treatments may vary.