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0 0.5 1 1.5 2+ Mortality 33% Improvement Relative Risk c19early.com/mf Chen et al. Metformin for COVID-19 Prophylaxis Favors metformin Favors control
Chen, 120 patient metformin prophylaxis study: 33% lower mortality [p=0.46] https://c19p.org/chen3
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Clinical Characteristics and Outcomes of Patients With Diabetes and COVID-19 in Association With Glucose-Lowering Medication
Chen et al., Diabetes Care, doi:10.2337/dc20-0660
31 Jul 2020    Source   PDF   Share   Tweet
Retrospective 120 COVID-19 diabetes patients, showing non-statistically significantly lower mortality with existing metformin treatment.
risk of death, 33.0% lower, RR 0.67, p = 0.46, treatment 4 of 43 (9.3%), control 15 of 77 (19.5%), NNT 9.8, adjusted per study, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Chen et al., 7/31/2020, retrospective, China, Asia, peer-reviewed, 12 authors.
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