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Home   COVID-19 treatment studies for Convalescent Plasma  COVID-19 treatment studies for Conv. Plasma  C19 studies: Conv. Plasma  Conv. Plasma   Select treatmentSelect treatmentTreatmentsTreatments
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0 0.5 1 1.5 2+ Mortality -323% Improvement Relative Risk Mortality (b) -114% Ventilation -221% Hospitalization time 25% Improvement in Ct value 32% c19early.com/cp Bajpai et al. Conv. Plasma for COVID-19 RCT LATE Favors conv. plasma Favors control
Bajpai, 29 patient convalescent plasma late treatment RCT: 323% higher mortality [p=0.22], 221% higher ventilation [p=0.33], 25% shorter hospitalization [p=0.08], and 32% improved viral clearance [p=0.11] https://c19p.org/bajpai
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Efficacy of Convalescent Plasma Therapy compared to Fresh Frozen Plasma in Severely ill COVID-19 Patients: A Pilot Randomized Controlled Trial
Bajpai et al., medRxiv, doi:10.1101/2020.10.25.20219337 (Preprint)
27 Oct 2020    Source   PDF   Share   Tweet
Small RCT 29 patients in India, 14 treated with convalescent plasma, not showing significant differences with treatment.
risk of death, 323.0% higher, HR 4.23, p = 0.22, treatment 3 of 14 (21.4%), control 1 of 15 (6.7%), adjusted per study, 28 days, Cox proportional hazards.
risk of death, 114.3% higher, RR 2.14, p = 0.60, treatment 2 of 14 (14.3%), control 1 of 15 (6.7%), 7 days.
risk of mechanical ventilation, 221.4% higher, RR 3.21, p = 0.33, treatment 3 of 14 (21.4%), control 1 of 15 (6.7%), 7 days.
hospitalization time, 24.8% lower, relative time 0.75, p = 0.08, treatment 14, control 15.
relative improvement in Ct value, 32.5% better, RR 0.68, p = 0.11, treatment 14, control 15.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Bajpai et al., 10/27/2020, Randomized Controlled Trial, India, South Asia, preprint, 20 authors.
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