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0 0.5 1 1.5 2+ Hospitalization 39% Improvement Relative Risk c19early.com/mf Ando et al. Metformin for COVID-19 Prophylaxis Favors metformin Favors control
Ando, 28,093 patient metformin prophylaxis study: 39% lower hospitalization [p=0.04] https://c19p.org/ando
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Impact of overlapping risks of type 2 diabetes and obesity on coronavirus disease severity in the United States
Ando et al., Scientific Reports, doi:10.1038/s41598-021-96720-x
9 Sep 2021    Source   PDF   Share   Tweet
Retrospective 28,093 COVID+ patients in the USA, showing lower risk of hospitalization with metformin use.
risk of hospitalization, 39.0% lower, HR 0.61, p = 0.04, treatment 19 of 663 (2.9%), control 1,056 of 27,430 (3.8%), adjusted per study, multivariable, Cox proportional hazards.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Ando et al., 9/9/2021, retrospective, USA, North America, peer-reviewed, 6 authors, study period 1 January, 2020 - 30 November, 2020.
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